NMRFAM-SPARKY

Synopsis

A graphical NMR assignment and integration program for proteins, nucleic acids, and other polymers.

Description

SPARKY remains the most popular computer program for NMR operations, such as peak-picking and peak assignment, despite that fact that its originators have not released a new version since 2001 (Goddard & Kneller, SPARKY 3). NMRFAM has taken over the original Sparky from UCSF for the continuous development to implement advances in biomolecular NMR field.

SPARKY supports user-defined enhancements, and we have used these to develop new tools in support of our packages for automated protein assignment and structure determination. The added features support

(1) interfacing with servers offering new technologies,
(2) tools for data visualization and verification, and
(3) new protocols for maximizing the efficiency of NMR data analysis.

URL

http://www.nmrfam.wisc.edu/nmrfam-sparky-distribution.htm

Versions

NMRbox Version	Software Version
1.0.0	Build_05-27-2016,
2.0.0	Build_12-14-2016,
3.0.0	Build_12-14-2016, Build_07-07-2017,

Keywords

Chemical Shift Assignment
Peak Picking
Structure Determination
Structure Prediction
Utilities
Intrinsically Disordered Proteins (IDPs)
Automated Structure Determination
Automated Chemical Shift Assignment

Citations

NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy

Lee Woonghee, Markley John L, Tonelli Marco,

Bioinformatics. 2014; (): btu830