MODELLER

MODELLER


Synopsis

Homology or comparative modeling of protein three-dimensional structures.

Description

MODELLER is used for homology or comparative modeling of protein three-dimensional structures. The user provides an alignment of a sequence to be modeled with known related structures and MODELLER automatically calculates a model containing all non-hydrogen atoms. MODELLER implements comparative protein structure modeling by satisfaction of spatial restraints, and can perform many additional tasks, including de novo modeling of loops in protein structures, optimization of various models of protein structure with respect to a flexibly defined objective function, multiple alignment of protein sequences and/or structures, clustering, searching of sequence databases, comparison of protein structures, etc.

URL

https://salilab.org/modeller/

Versions

NMRbox Version Software Version
1.0.0 9.16-1,
2.0.0 9.17-1,
3.0.0 9.19-1,

Keywords

  • Homology Modeling

Citations

Comparative protein structure modeling using Modeller
Webb Benjamin, Sali Andrej,
Current Protocols in Bioinformatics. 2014; 47(5.6): 5.6.1-5.6.32